This presentation, led by Dr. Domingo Gonzalez Lamuno, explores the importance of physical activity and sharing practical advice when prescribing physical activity for PKU patients. It highlights how regular exercise and physical activity influence patient's metabolism and overall well-being and outlines key practical aspects.

Key topics include:

• Physical activity and general health in PKU patients and how it improves health condition;
• Exercise and adherence to supplements: exercise prescription can improve adherence to protein substitutes
• How to evaluate patient's fitness condition? To incorporate exercise as a vital sign.
•  Physical activity and exercise prescription in PKU - key practical aspects to be considered;